On the 17th of July Jamie graduated from the University of Liverpool with a PhD in Obesity and Endocrinology (Med) where his work focused on the pathophysiology and diagnosis of neuropathies, with an emphasis on the contribution of small nerve fibres.

During his PhD, he demonstrated that intra-epidermal nerve fibres can be processed using an automated immunohistochemistry staining platform, which he hopes may mitigate downstream barriers to take-up this diagnostic technique.

He has also implemented other techniques such as corneal confocal microscopy for quantifying and detecting small fibre pathology in participants with fibromyalgia syndrome, idiopathic, diabetic, and chemotherapy-induced peripheral neuropathy.

Furthermore, he was able to perform quantitative sensory testing and study symptomatology as part of deep phenotyping studies in these conditions. His research also included the use of a large dataset to identify brain alterations as identified by magnetic resonance imaging in diabetes mellitus and found that these may predate overt end-organ damage. To better understand the role corneal confocal microscopy may have to improve in the diagnosis of neuropathies, he has undertaken a Cochrane Diagnostic Test Accuracy Systematic Review to determine the utility of corneal confocal microscopy in the diagnosis of diabetic sensorimotor polyneuropathy which he anticipates will inform clinical practice and future studies